Our research impact

Our cutting-edge research by our creative talents has produced a large number of discoveries and inventions. A sample our discoveries and inventions:

  • We laid the foundation in the 1920’s for the systematic approach in periodontal disease that incorporates connective tissue biology and microbiology (H.K. Box).
  • Our research on the intracellular pathway of collagen degradation altered the prevailing view of physiological collagen turnover (A.R. Ten Cate).
  • A.H. Melcher’s research on periodontal wound healing established the necessary criteria for successful dental implantation.
  • G. Zarb’s work in dental implantology irrefutably revolutionized fixed tooth replacement.
  • B. Sessle charted the frontier of orofacial pain and neuromuscular research
  • The Institution’s Burlington Growth Centre (founded by R. Moyers and F. Popovitch), which contains one of the largest and most comprehensive longitudinal records of craniofacial growth and development in the world provided critical resources to orthodontics research
  • Our revolutionary quality of life questionnaire (“Oral Health Impact Profile”; D. Locker, 1990’s), which has been translated into numerous languages used in dental education across the globe, is used worldwide to measure the subjective impact of oral disease and dental interventions
  • We are trying to improve the oral health of Canada’s Indigenous population and to uncover the biological basis for the impact of socio-economic status on oral health – a novel undertaking in this field (Gomaa, Can J Publ Health 108:e224-28, 2017). 
  • We are the first dental school to create a link between research in fibrosis in the periodontium and in the kidney, lung, heart, and skin. Our influential fibrosis research attracted >$10M funding in one year solely to support this body of work. See the news story Fibrosis research at the faculty of dentistry receives major funding boost.
  • Williams Probe: the benchmark of periodontal probes to examine periodontal pockets. To date, it has been one of the most popular periodontal probe used (C. Williams).
  • Zinc polycarboxylate cement: one of few materials available to this day that reliably bonds to tooth surfaces (D. Smith).
  • Acrylic Bone Cement:  D. Smith’s collaboration with Sir J. Charnley bone cement led to the first successful cemented prostheses, which revolutionized orthopaedic surgery. It continues to be used today to achieve long-term fixation of the metal and plastic components used as a treatment for arthritis that was previously unachievable.
  • B. Pilliar created the cementless hip implant prosthetic device.
  • P. Santerre invented ‘Endexo’ a surface-modifying material that can be applied to medical tubing to prevent blood from sticking and clotting (> 60 patents), winning the 2017 Governor General’s Innovation Award.
  • J.E. Davies developed OsteoScaf, a human trabecular bone-like scaffold that has successfully treated alveolar bone defects in dental patients and alveolar bone clefts and novel sources of human mesenchymal stromal cells with immunomodulatory properties.
  • B. Hinz ‘s research discovered a high throughput heart-cell wrinkling platform to develop safer drugs.
  • Y. Finer developed antibacterial silica self-assembled medical and dental materials.
  • M. Glogauer’s research produced a chairside diagnostic tool for periodontal disease.
  • H. Lawrence leads a team to study the impact of cannabis use on indigenous oral health.