Christopher McCulloch


Canada Research Chair in Matrix Dynamics

Other Appointments

B.Sc., D.D.S., Ph.D., F.R.C.D(C)


Dr. McCulloch’s research explores signaling systems that regulate periodontal and cardiac connective tissues. The ultimate goal of his research is to define new therapies for diseases ranging from chronic periodontitis to cancer. 


Tier 1Canada Research Chair (CRC) in Matrix Dynamics (20016; 2013)  

Distinguished Alumni Award; Faculty of Dentistry, University of Toronto (2011)

International Association of Dental Research (IADR); Distinguished Scientist Award for Research in Oral Biology, United States (2009)  

International Association of Dental Research (IADR); Hatton Award (2009)

Fellow, Canadian Academy of Health Sciences, (2007 – present)

International Association of Dental Research (IADR); Hatton Award (1998)

Select Publications

Mezawa M, Pinto VI, Kazembe MP, Lee WS, McCulloch CA.  Filamin A regulates the organization and remodeling of the pericellular collagen matrix.  FASEB J. 2016 Jul 12.  Epub ahead of print. 

Coelho NM, McCulloch CA.  Contribution of collagen adhesion receptors to tissue fibrosis.  Cell Tissue Res. 2016 Sep;365(3):521-38.

Civitarese RA, Talior-Volodarsky I, Desjardins JF, Kabir G, Switzer J, Mitchell M, Kapus A, McCulloch CA, Gullberg D, Connelly KA. The a11 integrin mediates fibroblast- extracellular matrix- cardiomyocyte interactions in health and disease. Am J Physiol Heart Circ Physiol. 2016 Jul 1;311(1):H96-H106.